This enhanced immune response can result in the secretion of cytokines and chemokines that recruit and activate other immune cells, such as T cells and natural killer (NK) cells, which collectively strengthen the body’s defense against tumor growth; Activated white blood cells 2 can release immune factors like TNF and interferon-gamma, which directly inhibit tumor cell proliferation, survival, and induce cell death (apoptosis). The gene discussed is IFNG; the disease is neoplasm.