This includes promoting local inflammation, which further curtails tumor expansion and metastasis; White blood cells 2 can trigger apoptosis in tumor cells by releasing TRAIL and granzyme B. This process activates apoptotic pathways in tumor cells, leading to their death and hindering further tumor progression; Activated white blood cells 2 can produce factors that disrupt angiogenesis, thereby limiting the formation of new blood vessels that tumors rely on for nutrients and oxygen. This evidence concerns the gene TNFSF10 and neoplasm.