Precise single-cell DNA damage analysis using the alkaline comet assay revealed that KRAS WT NSCLC cells exhibit greater sensitivity to cisplatin-induced DNA damage compared with KRAS mutant lung cancer cells (Figure 1C and Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI185149DS1). This evidence concerns the gene KRAS and lung carcinoma.