In a recent study, using Olink Explore to quantify 1463 proteins in CSF and plasma from 143 people with early stage MS and 43 healthy controls, it was found that the top proteins (MZB1, CD79B, CD27, and TNFRSF13B) with the ability to discriminate MS from healthy individuals are all expressed in B cells [145]. This evidence concerns the gene TNFRSF13B and myeloid sarcoma.