However, despite the promising pro‐myogenic effect of CYTOR overexpression, CYTOR was shown to be highly expressed in a variety of tumors including gastric cancer,[21, 22] colon cancer,[23] lung adenocarcinoma,[24, 25] breast cancer[26, 27] and reported to increase tumorigenesis, including invasion, metastasis, malignant proliferation, and glycolysis.[28] Overexpression of CYTOR is closely related to clinicopathological characteristics, such as tumor stage, lymph node metastasis/infiltration, and poor prognosis of tumor patients. This evidence concerns the gene CYTOR and metastatic malignant neoplasm in the lymph nodes.