It primarily recognizes the 5’ UTR of m6A methylated RNA, enhances the stability of the eukaryotic translation initiation factor 3 subunit A (eIF3A) complex through eukaryotic translation initiation factor 2 alpha kinase 2 (eIF2AK2), and promotes target gene translation efficiency.75 Additionally, YAP-mediated CRC cell invasion and proliferation were reduced when YTHDF3 was knocked down.76 YTHDC1/2 presence bolsters intestinal health. The gene discussed is YTHDF3; the disease is colorectal carcinoma.