Marfan Syndrome (MFS) is the most common monogenetic autosomal-dominant disorder of connective tissue due to mutations in the gene encoding for fibrillin-1 (Fbn1) that presents with manifestations in many organs and systems in the body, resembling phenotypes of premature aging (Canadas et al., 2010a; Canadas et al., 2010b). Here, FBN1 is linked to Marfan syndrome.