For instance, in the scRNA-seq datasets of immune cells and tumor cells from CRA001160, a total of 566 experimentally validated genes of “immune system process” (GO:0002376) were recalled, and among them, 242 recalled genes, such as IRF7, CD58 and IFNAR1, were only discovered in immune cell scRNA-seq data; 138 recalled genes, such as CD47, CX3CL1 and CCL28, were only discovered in tumor cell scRNA-seq data (Fig. 3A). Here, IRF7 is linked to neoplasm.