EGFR and glioblastoma: Although EREG was identified by random forest regression only in the Intellance-2 dataset, the gene was downregulated in EGFR-amplified samples in both the TCGA-GBM (LFC = −1.92, FDR-adjusted P-value = 1.24e−06) and Intellance-2 (LFC = −2.53, FDR-adjusted P-value = 1.16e−05) datasets using DGE.