Head and neck PGLs were statistically seen more in SDH-D carriers compared with SDH-B mutations, which are prevalent in intra-abdominal extra-adrenal tumors, although malignant tumors are more frequent in SDH-B mutations.1168Ga-DOTATATE showed a significantly superior detection rate compared with other functional and anatomical imaging modalities in the evaluation of SDH-B-related metastatic PGLs.12 Here, SDHD is linked to cancer.