NCOA1–3 (SRC1–3) have been implicated in heart developmentand are associated with noncompaction cardiomyopathy[237] and pressure overload-inducedangiogenesis in mice[238].NCOA1–3 proteins are highly expressed in cardiac fibroblasts in adultmice[239]. This evidence concerns the gene NCOA1 and Noncompaction cardiomyopathy.