ACOT7 and neoplasm: Metastatic cancer treatment was made possible by fucoidan-coated nanomaterials that triggered platelet-targeting micelles, which successfully tracked tumor cells and changed the microenvironment in primary tumor and premetastatic organs [Fig. 11C].223 In a similar study, using tumor-targeted, self-assembled nanoparticles, Yang et al. regulated mitochondrial metabolism and BACH, a transcription factor with elevated expression in tumors of triple-negative breast cancer patients.