Furthermore, to ascertain AMD‐like changes in the mLST8 KI retina, immunohistochemistry on 9‐month‐old WT and mLST8 KI mouse retinal sections was performed to assess APOE expression, which is prominently observed in human AMD donors as well as mouse models, and is thought to be a critical marker for drusen or drusen‐like deposits in early/dry AMD. The gene discussed is MLST8; the disease is age-related macular degeneration.