MLST8 and age-related macular degeneration: Therefore, in this study, we have attempted to demonstrate that the specific overexpression of mammalian lethal with Sec13 protein 8 (mLST8) in the mouse RPE activates both mTORC1 and mTORC2, inducing epithelial–mesenchymal transition (EMT)‐like changes and subretinal/RPE deposits resembling early AMD‐like pathogenesis.