After that, we measured the contents of inflammatory molecules TNF- α and IL-6 in the serum of mice in the BAT control group and BAT ectomy group (Fig. 7b), and found that compared with the BAT control group, the contents of TNF- α and IL-6 in the serum of CLP mice in the BAT ectomy group were significantly increased, suggesting that the systemic inflammation of mice was significantly aggravated, which was consistent with our previous conclusion that BAT ectomy aggravated sepsis in mice. Here, TNF is linked to Sepsis.