Scenarios include NTRK fusion genes, such as NTRK1, NTRK2, and NTRK3 (encoding tropomyosin receptor kinases, TrkA, TrkB, and TrkC, respectively),239,240 that link the tyrosine kinase domain with a 5’ fusion partner (over 50 partners across cancers). The gene discussed is NTRK3; the disease is cancer.