A more recently described progeria, Néstor-Guillermo progeria syndrome (NGPS), is caused by a recessive alanine to threonine amino acid substitution at position 12 (p.Ala12Thr) in the BANF1 gene, encoding the 10 KDa protein barrier-to-autointegration factor (BAF)3,4. This evidence concerns the gene BANF1 and Nestor-Guillermo progeria syndrome.