Building upon our prior work, which linked the Ang-(1-7)/MAS axis to ccRCC cell migration [34], our current findings illustrate MAGI3’s ability to suppress cell proliferation mediated by Ang-(1-7)/MAS through ERK pathway inhibition in renal cells (Figs. 3 and 4, Supplementary Fig. 2). This evidence concerns the gene ANG and nonpapillary renal cell carcinoma.