We recently found that the retinas of patients with MCI (due to AD) and/or AD dementia exhibit significant increases in pathogenic p-tau at specific epitopes, including S202/T205, S214, S396, S404, and T231, as well as citrullinated R209-tau and tau oligomers (T22-positive), alongside PHF+ and MC-1+ pretangle and mature tau tangles. This evidence concerns the gene MAPT and Alzheimer disease.