In addition, pS396-tau and Oligo-tau laden RGC counts were strongly correlated with ABC disease severity scores (Fig. 5i-k; r = 0.70–0.73, P = 0.0002 − 0.0001), with strong associations remaining when analyzed for MCI (due to AD) and AD patients only (Fig. 5k). Here, MAPT is linked to Alzheimer disease.