MAPT and Alzheimer disease: Interestingly, analyses per retinal subregions detected stronger associations to AD-brain pathology for central retinal pS396-tau+ RGCs and mid-peripheral Oligo-tau+ RGCs (Table 2), with a very strong association between mid-peripheral Oligo-tau+ RGCs and brain NFTs (rS=0.81, P < 0.0001).