However, our analyses of TCGA data revealed that there is no enrichment for other commonly recurrent ccRCC-specific gene mutations, including PBRM1, BAP1, SETD2, ARID1A, TP53, PTEN or MTOR in Y chromosome-deficient ccRCCs (data not shown). The gene discussed is PBRM1; the disease is nonpapillary renal cell carcinoma.