With respect to the hormone receptor pathway, CS for Basal-like BRCA is highest (CS = 1) and is equal to 0.67 and 0.33 in Luminal A and B and Her2-enriched cancer, partly due to the reason that all hormone receptors are likely to have a down-expression in Basal-like BRCA while the associations among hormone receptors are more complicated and diverse in the other two groups. The gene discussed is ERBB2; the disease is cancer.