GALT deficiency originates the accumulation of Gal‐1‐P and is known to play a fundamental role in classic galactosemia pathogenesis; on the other hand, patients suffering from GALK1 deficiency (OMIM 230200), who accumulate several galactose metabolites but not Gal‐1‐P, present mild symptoms, essentially early‐onset cataracts but not brain and ovarian complications, the major and until now irresolvable problem affecting GALT‐deficient patients. The gene discussed is GALT; the disease is cataract.