In gliomas, elevated TMEM71 expression correlates with enhanced immune responses, while in breast cancer, reduced TMEM71 levels have been noted, with studies showing its overexpression can curb cell proliferation and migration.26, 27 TMEM71 is also a component of a prognostic model for papillary renal cell carcinoma.28 The gene discussed is TMEM71; the disease is central nervous system cancer.