Using mice intracerebrally challenged with B. pertussis, a study has shown the effect of IgA contained in human colostrum on bacteria neutralization.18 PT-specific IgA and IgG from maternal breastmilk have also been shown to remain stable in the infant gastrointestinal tract during digestion.19 Increasing pertussis-specific IgA in breastmilk through maternal vaccination could plausibly increase protection against pertussis in the neonate, but the impact of timing of vaccination on pertussis antibody concentration has not previously been explored. The gene discussed is CD79A; the disease is pertussis.