CCL18 and cancer: In noncancerous tissue, top DEGs included chemokine CCL18 (fold change [FC] = 6.54; FDR = 6.36 × 10−2), which is released by tumor-associated macrophages to promote cancer cell invasion, and coagulation factor F8A3 (FC = 3.18; FDR = 1.36 × 10−4).