Gastrin‐SiO2 microspheres (20 mg kg−1 day−1, 80 μL/10 g), administered by gavage (10–20 s), did not affect the mRNA expression of inflammatory factors (TNFα, MCP‐1, MCP‐2, IL‐1β, and IL‐6) in the intestine (Figure 5H) and colon cancer promoting markers in the serum (CEA, CA199, and PSA) (Figures 5I–K). The gene discussed is CEACAM5; the disease is colonic neoplasm.