Gastrin‐SiO2 microspheres (20 mg kg−1 day−1, 80 μL/10 g), administered by gavage (10–20 s), did not affect the mRNA expression of inflammatory factors (TNFα, MCP‐1, MCP‐2, IL‐1β, and IL‐6) in the intestine (Figure 5H) and colon cancer promoting markers in the serum (CEA, CA199, and PSA) (Figures 5I–K). This evidence concerns the gene KLK3 and colonic neoplasm.