For all these reasons, drug loaded albumin nanoparticles (NPs)are frequently preferred in the field of controlled drug deliverystudies and in clinical studies.9−14 Abraxane, an albumin-based NP formulation of paclitaxel, is thefirst human serum albumin (HSA) based drug approved by the FDA in2005 for the treatment of breast cancer, and it has been also usedin the treatment of nonsmall lung cancer, pancreatic cancer, and gastriccancer.14−16. This evidence concerns the gene ALB and breast cancer.