SBF2 and glioblastoma: High levels of SBF2‐AS1 in exosomes of TMZ‐resistant GBM cells allowed TMZ resistance to spread in GBM cells undergoing chemotherapy GBM cells enriched exosomes by secreting oncogenic lncSBF2‐AS1, which reorganises the tumour microenvironment and upgrade chemotherapy rejection in GBM cells.