Combining NTRK1+/NTRK3+/RET+ CRC with known fusion partners (N = 13), the mean number of genomic co‐mutations was 68.3 ± 7.9 compared to the mean number of 11.8 ± 11.1 co‐mutations for all other RTK+ CRC (ALK, EGFR, FGFR1/2, ERBB4, FLT1/3/4, LMKT2, MET, NTRK2, PDGFR‐β, ROS1) with known fusion partners (N = 30, one sample with no recorded genomic co‐mutations, one duplicated sample). This evidence concerns the gene ALK and colorectal carcinoma.