High expression of PDF may potentially reduce the risk of BD (βbrain=-0.215, βblood=-0.318, βGETx=-0.317), while high expression of XPNPEP3 may potentially increase the risk of BD (βbrain=0.275, βblood=0.506, βGETx=0.266) (Figure 2). Here, XPNPEP3 is linked to Behcet disease.