Compared with healthy subjects, individuals with gallbladder stones had higher GHR values; compared with those without gallbladder stones, individuals with gallbladder stones were more prone to be female, older, Mexican American, other Hispanic, or non-Hispanic white, individuals with a history of hypertension, diabetes mellitus, higher BMIs, higher triglyceride indices, and higher fasting blood glucose values (all P < 0.05) (Table 1). Here, GHR is linked to diabetes mellitus.