Correlation analysis between circulating miR-22-3p levels and the traditional diagnostic tests for hypercortisolism reveals a positive correlation with serum cortisol levels post-ODST (rs=0.361, p=0.005) and UFC (rs=0.476, p<0.001), and a negative correlation with ACTH (rs=-0.351, p=0.006) in patients with ATs (Figure 6). The gene discussed is POMC; the disease is Andersen-Tawil syndrome.