We noted that endothelial Mct1 deficiency had no effect on plasma cholesterol levels either before (168.3 vs. 159.3 mg/dL for the sictl group and siMct1 group) or after (789.6 vs. 804.8 mg/dL for the sictl group and siMct1 group) the introduction of the WD. The gene discussed is SLC16A1; the disease is hyperinsulinemic hypoglycemia, familial, 4.