Although multiple data from TCGA LUSC and GEO databases indicate that high expression of PCDHGB7 is associated with poor prognosis, there is a potential contradiction in the prognostic role of PCDHGB7 in lung squamous cell carcinoma and adenocarcinoma, which requires further validation with larger sample sizes in the future. This evidence concerns the gene PCDHGB7 and squamous cell lung carcinoma.