It directly binds to CD38 and exerts its anti-tumor effects through multiple mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), direct induction of cellular apoptosis, complement-dependent cytotoxicity (CDC), and modulation of extracellular ectoenzyme activity (19). The gene discussed is CD38; the disease is neoplasm.