The CSF ANA was 1:100(normal is negative).Other laboratory test results including Procalcitonin(PCT), C-reactive protein(CRP), antiphospholipid antibody(APLA), tumor markers, and disseminated intravascular coagulation(DIC),anti-neutrophil cytoplasmic antibodies(ANCA) did not show significant abnormalities. The gene discussed is CRP; the disease is neoplasm.