also reported that nilotinib induced both parkin and LC3-II proteins in the lung of M. bovis infected animals at 63 d.p.i. In a natural infection, M. bovis leads to the overexpression of the Abelson tyrosine kinase (Abl), that inhibits parkin, which is crucial to promote ubiquitin accumulation around the bacilli for its elimination (92). The gene discussed is PRKN; the disease is infection.