α-syn: α-synuclein, cKO: conditional knockout, DA: dopaminergic, DLB: dementia with Lewy bodies, KD: knockdown, MPTP: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, OE: overexpression, p-Ub: phosphorylated ubiquitin, Tg: transgenic, TH: tyrosine hydroxylase, Trx: thioredoxin-1, ↑: increase, ↓: decrease. This evidence concerns the gene TH and Lewy body dementia.