Since several synaptic proteins have been reported to be degraded by eMI (Uytterhoeven et al., 2015), it is possible that α-synuclein undergoes degradation as well, and STK38-regulated microautophagy has been reported to prevent aging (Ogura et al., 2023), so further studies are warranted on the relationship between microautophagy and PD. The gene discussed is SNCA; the disease is Parkinson disease.