Comparatively, treatment with EcN-GLP-1 led to an increase in Alloprevotella, Escherichia, and Parasutterella (p < 0.05), along with a decrease in the levels of Helicobacter, Bacteroides, and Lactobacillus (p < 0.05) when compared to the T1DM group. This evidence concerns the gene GCG and type 1 diabetes mellitus.