Genes such as SlAGO1a, 1b, 4a, and 4b showed varying degrees of upregulation under tomato yellow leaf curl virus (TYLCV; Begomovirus coheni) infection and abiotic stress, indicating that tomato AGO proteins play an important role in regulating developmental signals and responding to biotic and abiotic stresses (Bai et al., 2012). The gene discussed is FBXW7; the disease is infection.