AKT1 and hepatocellular carcinoma: Through conducting Western blot, we found that the levels of β-catenin and p-AKT, as well as the downstream factors, including c-Myc and EpCAM, were decreased with the knockdown of SLC1A4 in Huh7 and HepG2 cells (Figure 2c), indicating the potential mechanism regulated by SLC1A4 in HCC.