Secondly, larvae with CRISPR/Cas9-induced mutations in agrp (n = 59) are at higher risk of being in Q1 vs. Q2 than sibling controls (n = 34), in line with agouti-related protein’s anticipated orexigenic activity, as well as with overexpression of agrp in adult zebrafish resulting in obesity, increased growth and adipocyte hypertrophy58. This evidence concerns the gene AGRP and obesity disorder.