In absence of adequate statistical power to detect an effect on whole-body adiposity, elevated lipid accumulation in the liver of larvae with one remaining bdnf allele could be considered directionally consistent with the obese phenotype observed in BDNF haploinsufficient humans43, as well as with diabetic db/db mice showing less hepatic steatosis upon subcutaneous injection with Bdnf44. Here, BDNF is linked to fatty liver disease.