Diagnostic criteria for acute cholecystitis [4] are based on the presence of: (1) local inflammation (Murphy’s sign, RUQ mass, pain, tenderness); (2) systemic inflammation (fever, elevated CRP, elevated WBC); (3) imaging findings (wall thickening > 3 mm, wall edema, gallbladder distension > 40 mm, positive sonographic Murphy sign, pericholecystic and perihepatic fluid) [5]. This evidence concerns the gene CRP and Cholecystitis, Acute.