Unlike the conventional N-glycan types (oligomannosidic-, hybrid-, complex-type), the less investigated non-canonical paucimannosidic-type glycans, that is, Man1-3GlcNAc2Fuc0-1 (short-hand M1-M3F) (42, 43, 44) were strongly elevated in the N-glycome of CRC TUM (CRC stage I-IV: 13.5–15.4%, NAT: 6.7%) and in PBMCs (CRC stage I–IV: 19.5–27.1%, normal controls: 14.9%) as determined using quantitative glycomics (Fig. 1C, see Supplemental Tables S4 and S5 for data and Supplemental Data S1 for spectral evidence). This evidence concerns the gene BRD2 and colorectal carcinoma.