In HBV-infected distal non-tumor liver tissues from hepatocellular carcinoma patients, colocalization of the PGLYRP2/HBV capsid complex with CD68, a pan-macrophage marker, was demonstrated using multiplex immunofluorescence staining, suggesting the presence of the complex within liver macrophages (Figure 6C). Here, CD68 is linked to hepatocellular carcinoma.