VHL and renal cell carcinoma: Interestingly, thesize of the large RCC in patients harboring VHL pathogenicvariants (n = 9) was significantly greater than that in patients withVHL likely pathogenic (n = 7) variants (5.4 cm [3.65 to6.6] vs. 2.9 cm [2.45 to 3.35]; p = 0.008).