In patient #3, a 59‐year‐old female presenting with a BMI of 35.6 kg/m2, hypertriglyceridemia (serum triglycerides: 231 mg/dL), SLD and hepatic fibrosis, and a positive family history, we identified a rare heterozygous pathogenic variant (NM_000237: p.G181D) in LPL gene, accounting for a genetic diagnosis of familial combined hyperlipidemia, characterised by increased levels of serum cholesterol and triglycerides. The gene discussed is LPL; the disease is hypertriglyceridemia.