FOXP3 and immune dysregulation-polyendocrinopathy-enteropathy-X-linked syndrome: IPEX [XL forkhead box P3 (FOXP3) mutations] and IPEX-like syndromes [AR Cluster of Differentiation 25 (CD25) deficiency, AR/AD STAT5b deficiency, AD STAT1 GOF, AR Itchy E3 Ubiquitin Protein Ligase (ITCH) deficiency] are included in the category of Treg-opathies, namely disorders caused by genetic mutations lead to defects in molecules essential for the development, survival, and/or function of regulatory T (Treg) cells [3▪,15].