Model 3, further adjusted for SII, TyG, bilirubin, BMI, cotinine levels, AST, ALT, estimated glomerular filtration rate (eGFR), history of cardiovascular disease, stroke, alcohol consumption, smoking, and diabetes, yielded an OR of 0.989 (95% CI: 0.984, 0.994; p < 0.001). The gene discussed is GPT; the disease is cardiovascular disorder.