By increasing the expression of PD-L1, hsa_circ_ 0136666 (81), hsa_circ_ 0020397 (82), CDR1-AS (83), and circEIF3K (84) promotes the carcinogenesis and immune evasion of CRC, potentially providing new insights into the molecular immunopathogenesis of CRC. Here, CD274 is linked to colorectal carcinoma.