AGO2 and atherosclerosis: Pei et al. established an in vitro atherosclerosis model using ox-LDL to stimulate human umbilical vein endothelial cells (HUVECs) and vascular smooth muscle cells (VSMCs), investigating the potential functions of the CASC7/miR-21 axis in TLR4/NF-κB and PI3K/AKT signaling pathways (Canfrán-Duque et al., 2017).