H19 and metabolic disease: Recently, a growing number of researches have focused on the relationship between RNA and gut microbiota in metabolic disorders, for example, The main RNAs associated with metabolic heart disease are miR-21, miR-126, miR-33, lncRNA-H19, lncRNA-H19, lncRNA-ANRIL (Krichevsky and Gabriely, 2009; Olivo-Martínez et al., 2024; Surina et al., 2021).