AKT1 and esophageal squamous cell carcinoma: Zhao et al. confirmed that miR-574-5p promotes ESCC cell proliferation by binding to CTDSP1 mRNA’s 3'-UTR, miR-574-5p suppresses its expression, leading to decreased CTDSP1 protein levels and increased AKT phosphorylation, which is a hallmark of tumor cell survival and proliferation (Zhao C. et al., 2022).